In Vivo Nutrient Uptake by Head and Neck Cancers1
نویسندگان
چکیده
The arteriovenous uptake differences for glucose, lactate, pyruvate, />'hydroxybutyrate, and acetoacetate were measured in vessels across squa mine, cell carcinomas in ten selected patients with tumors of the head and neck. All tumors measured took up glucose, pyruvate, 0-hydroxybutyrate, and acetoacetate. They could either produce, take up, or main tain a constant level of lactate. These tumors demonstrate a heterogeneous affinity for various metabolites, including ketone bodies which are ele vated in the nutritionally depleted, tumor-burdened patient.
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